Tomato and lemon extracts synergistically improve cognitive function by increasing brain-derived neurotrophic factor levels in aged mice

• DOI: 10.1017/s0007114523002301
• Publication Date: 2023-11-29T02:02:51Z
• Authors: Kyeong-No Yoon; Yidan Cui; Qing-Ling Quan; Dong Hun Lee; Jang-Hee Oh; Jin Ho Chung
• Keywords: Doublecortin; Cognitive Decline; Cognitive deficit

Brain ageing, the primary risk factor for cognitive impairment, occurs because of accumulation age-related neuropathologies. Identifying effective nutrients that increase function may help maintain brain health. Tomatoes and lemons have various bioactive functions exert protective effects against oxidative stress, ageing cancer. Moreover, they been shown to enhance function. In present study, we aimed investigate tomato lemon ethanolic extracts (TEE LEE, respectively) their possible synergistic on enhancement neurogenesis in aged mice. The molecular mechanisms underlying effect TEE LEE were investigated. For