Postural Instability and Cognitive Dysfunction in Early Parkinson's Disease

• DOI: 10.1017/s0317167100013986
• Publication Date: 2014-12-12T10:03:41Z
• Authors: Jong Moon Lee; Seong-Beom Koh; Sung Won Chae; Woo-Keun Seo; Do Young Kwon; Ji Hyun Kim; Kyungmi Oh; Jong Sam Baik; Kun Woo Park
• Keywords: Posturography; Postural instability; Neuropsychological test

Background: Postural instability is one of the most disabling features Parkinson's disease, usually occurring in late and advanced stages. The aim this study was to investigate postural performance early-stage de novo disease patients with no clinical using computerized dynamic posturography. We sought understand relationship between sway severity quantitatively measured by posturography cognitive impairment patients. Method: Thirty-one subjects 20 healthy controls were assessed protocol sensory organization test motor control test. A neuropsychological assessment also administered. Results: mean equilibrium score for vestibular input ratio significantly correlated Hoehn-Yahr stage. No associations latency any condition stage found. mini-mental status examination scores. There a significant correlation large backward translation correlations visual perception/construction/ memory battery verbal word learning test, controlled association translation. Conclusion: These findings showed present (Hoehn-Yahr 2-2.5) disease. found close function