Current epidemiological aspects of human parvovirus B19 infection during pregnancy and childhood in the western part of Germany

• DOI: 10.1017/s095026880600731x
• Publication Date: 2006-10-26T07:28:04Z
• Authors: M. ENDERS; A. WEIDNER; G. ENDERS
• Keywords: Immunoglobulin M

SUMMARY This investigation was undertaken to provide detailed information on the epidemiology of human parvovirus B19 (B19) infection during pregnancy and childhood in western part Germany. Between 1997 2004, 40 517 sera from pregnant women aged 17–45 years 6060 children young adults were tested for IgG IgM our laboratory. In women, both history a ‘specific’ (OR 7·7, 95% CI 5·2–11·4) ‘non-specific’ rash 3·3, 1·5–7·1) predictive positivity. The prevalence 69·2% (4097/5924) subgroup asymptomatic screened antibodies. children, age-specific IgG-positivity rate increased 12·2% (66/541) at 2 age 71·9% (396/551) those older than 10 years. conclusion, Germany is higher then previously reported. Contact with 3–10 major risk factor exposure B19. Pregnant should also be evaluated acute infection.