Higher Healthy Lifestyle Score is associated with lower presence of non-alcoholic fatty liver disease in middle-aged and older Chinese adults: a community-based cross-sectional study

• DOI: 10.1017/s1368980021000902
• Publication Date: 2021-02-26T10:52:30Z
• Authors: Yun-yang Deng; Qing-wei Zhong; Hai-li Zhong; Feng Xiong; Yue-bin Ke; Yu-ming Chen
• Keywords: Cross-sectional study

Abstract Objective: Previous studies have reported inverse associations between certain healthy lifestyle factors and non-alcoholic fatty liver disease (NAFLD), but limited evidence showed the synergistic effect of those lifestyles. This study examined relationship a combination lifestyles, expressed as Healthy Lifestyle Score (HLS), with NAFLD. Design: A community-based cross-sectional study. Questionnaires body assessments were used to collect data on six-item HLS (ranging from 0 6, where higher scores indicate better health). The consists non-smoking (no active or passive smoking), normal BMI (18·5–23·9 kg/m 2 ), physical activity (moderate vigorous ≥ 150 min/week), diet pattern, good sleep insomnia <6 months) no anxiety (Self-rating Anxiety Scale < 50), one point each. NAFLD was diagnosed by ultrasonography. Setting: Guangzhou, China. Participants: Two thousand nine hundred eighty-one participants aged 40–75 years. Results: overall prevalence 50·8 %. After adjusting for potential covariates, associated lower presence OR subjects (3, 4, 5–6 v . 0–1 points) 0·68 (95 % CI 0·51, 0·91), 0·58 0·43, 0·78) 0·35 0·25, 0·51), respectively ( P -values 0·05). Among six items, strongest contributors. Sensitivity analyses that association more significant after weighting HLS. beneficial remained excluding any components replacing waist circumference. Conclusions: Higher NAFLD, suggesting pattern might be health.