Bioaccessibility of Apple Polyphenols from Peel and Flesh during Oral Digestion

• DOI: 10.1021/acs.jafc.1c08130
• Publication Date: 2022-03-31T13:27:51Z
• Authors: Julia A.H. Kaeswurm; Melanie R. Burandt; Pia S. Mayer; Leonie V. Straub; Maria Buchweitz
• Keywords: Digestion; Flavones; Flesh; Flavonols

Health benefits of apple polyphenols for different chronic diseases are postulated. To exert bioactive properties, absorption into the body is required (bioavailability), which strongly influenced by matrix release (bioaccessibility). For seven varieties, in vitro experiments with simulated saliva fluid (SSF) and ex vivo digestion centrifuged human were conducted. Polyphenol characterization (high-performance liquid chromatography-tandem mass spectrometry) quantification (high performance chromatography-diode array detection) was related to an aqueous methanolic extraction. A polyphenol 63-82% from flesh 42-58% peel estimated. While hydroxycinnamic acid derivatives released total, a significant retention observed flavanes flavones. In particular, procyanidins retained increasing molecular weight. The data reveal considerable during oral digestion; however, differences among varieties as well obvious. Due negligible between both media, supported use SSF instead further experiments.