Steroidal Saponins─New Sources to Develop Potato (Solanum tuberosum L.) Genotypes Resistant against Certain Phytophthora infestans Strains

• DOI: 10.1021/acs.jafc.2c02575
• Publication Date: 2022-06-09T17:46:25Z
• Authors: Sebastian Baur; Nicole Bellé; Oliver Frank; Sebastian Wurzer; Stefan Alexander ...; Tobias Fromme; Remco Stam; Hans Hausladen; Thomas Hofmann; Ralph Hückelhoven; Corinna Dawid
• Keywords: Phytophthora infestans; Solanum tuberosum; Industrial crop

Plant pathogens such as Phytophthora infestans that caused the Irish Potato Famine continue to threaten local and global food security. Genetic chemical plant protection measures are often overcome by adaptation of pathogen population structures. Therefore, there is a constant demand for new, consumer- environment-friendly strategies. Metabolic alterations induced P. in foliage tubers six different potato cultivars were investigated. Using combination untargeted metabolomics, isolation techniques, structure elucidation MS 1D/2D-NMR experiments, five steroidal glycoalkaloids, oxylipins, four saponins identified. As showed antioomycete but no hemolytic activity, they may thus be considered probably safe target substances enrichment breeding programs disease resistance lead structures production nature-derived synthetic antioomycetes.