Pheophorbide-a as a Light-Triggered Liposomal Switch: For the Controlled Release of Alpinia galanga (A. galanga) Essential Oil and Its Stability, Antioxidant, and Antibacterial Activity Assessment

• DOI: 10.1021/acs.jafc.2c07082
• Publication Date: 2023-01-11T15:32:58Z
• Authors: Xiangzhen Ge; Yayun Hu; Huishan Shen; Wei Liang; Zhuangzhuang Sun; Xiuyun Zhang; Wenhao Li
• Keywords: Pheophorbide A; Zeta potential; Dispersity

In this study, Alpinia galanga essential oil liposomes (EO-Lip) were prepared with soybean lecithin and cholesterol as wall materials. A light-responsive liposome (EO-PLip) was designed for the controlled release of A. based on properties Pheophorbide-a. The dependence Pheophorbide-a illumination time proved by UV spectroscopy. Characterization techniques such spectroscopy, transmission electron microscopy, Fourier transform infrared spectroscopy demonstrated that oils successfully encapsulated in liposomes. Moreover, particle size EO-PLip 166.30 nm, polydispersity index 0.22, zeta potential -49.50 mV, encapsulation efficiency 30.83%. Both EO-Lip EO-Plip have high sustained-release effects showed characteristics under stimulation. had good storage stability at 4 °C 28 d. excellent transient antioxidant bacteriostatic ability to respond light slow release. This provided a platform might be used potent controllable solution.