Perfluoroalkyl Group-Covered Organosilica Films for the Sensitive Detection of Sulfonylurea Herbicides in Laser Desorption/Ionization Mass Spectrometry

• DOI: 10.1021/acs.jafc.2c09077
• Publication Date: 2023-03-10T10:56:12Z
• Authors: Yuri Yamada; Masakazu Murase; Yasutomo Goto; Norihiro Mizoshita
• Keywords: Sulfonylurea; Surface Modification

Simple and rapid screening of agrochemicals greatly contributes to food environmental safety. Matrix-free laser desorption/ionization mass spectrometry (LDI-MS) is an effective tool for high-throughput analysis low-molecular-weight compounds. In this study, we report a UV-laser-absorbing organosilica film the sensitive detection various sulfonylurea herbicides using LDI-MS. Organosilica films with fluoroalkyl groups on organic part are fabricated, followed by additional modification silica moiety coupling agent cover surface hydrophobic groups. Nanoimprinting conducted impart nanostructures enhance LDI performance. The fabricated nanostructured accomplish cyclosulfamuron azimsulfuron at concentrations as low 1 fmol μL–1. applicability confirmed recovery ethametsulfuron-methyl from pea sprouts (Pisum sativum) hydroponically grown in herbicide-spiked water 0.5 ppm.