Comprehensive Engineering Strategies for Heterologous Production of Zealexin A1 in Saccharomyces cerevisiae

• DOI: 10.1021/acs.jafc.4c02595
• Publication Date: 2024-08-14T09:10:36Z
• Authors: Yukun Li; Ran Li; Jianjun Ge; Shengxin Nie; Ruiqi Chen; Xiaoguang Yan; Jianjun Qiao
• Keywords: Heterologous; Metabolic Engineering; Heterologous expression

Zealexin A1 is a nonvolatile sesquiterpene phytoalexin, which not only exhibits extensive antifungal and insecticidal activities but also has the ability to enhance drought resistance of plants, thus potential applications in agricultural food fields. In this study, biosynthetic pathway zealexin was constructed