Prediction of Potential Risk for Ten Azole and Benzimidazole Fungicides with the Aryl Hydrocarbon Receptor Agonistic Activity to Aquatic Ecosystems

• DOI: 10.1021/acs.jafc.4c09545
• Publication Date: 2024-12-31T14:01:22Z
• Authors: Chao Shen; Xiaoyan Ding; Wenhua Rao; Jinfeng Hu; Tao Lin; Xian-Zhi Zhou; Yongquan Zheng; Fengshou Dong; Guocheng Fan
• Keywords: Azole; Benzimidazole

Azole and benzimidazole fungicides are widely used agrochemicals to prevent treat fungal growth frequently detected in aquatic environments. Here, we aimed assess the ecological risks of ten currently azole fungicides, which with aryl hydrocarbon receptor (AhR) agonistic activity, their transformation products (TPs). We obtained over 400 types aerobic TPs for fungicides. Some (approximately 26.7%) exhibited potential AhR activity toxicity different species. Meanwhile, some compounds chlorine element benzene ring structure environmental persistence mobile ability. Several them were environments, posing ecosystems. These harmful should be given attention. This study provides important insight into caused by can provide theoretical guidance pollution control.