Whole Egg Consumption Prevents Diminished Serum 25-Hydroxycholecalciferol Concentrations in Type 2 Diabetic Rats

• DOI: 10.1021/acs.jafc.5b04347
• Publication Date: 2015-12-17T14:44:26Z
• Authors: Samantha K. Jones; Gar Yee Koh; Matthew J. Rowling; Kevin L. Schalinske
• Keywords: Male; 0301 basic medicine; 2. Zero hunger; Eggs; Rats; Rats, Zucker; Disease Models, Animal; 03 medical and health sciences; Diabetes Mellitus, Type 2; Animals; Humans; Vitamin D; Calcifediol

Type 2 diabetes (T2D) is characterized by vitamin D deficiency owing to increased urinary loss of 25-hydroxycholecalciferol (25D). Whole eggs are a rich source D, particularly 25D, the circulating form that reflects status. Zucker diabetic (type 2) fatty (ZDF) rats and their lean counterparts were fed casein- or whole egg-based diets for 8 weeks. egg consumption attenuated both hyperglycemia hypertriglyceridemia, as well reduced weight gain in ZDF compared casein-fed rats. Circulating 25D was lower controls; however, exhibited same concentration These data suggest dietary can attenuate metabolic anomalies, maintain normal concentrations T2D This finding may support new recommendations targeting prevention T2D.