Grape Pomace, an Agricultural Byproduct Reducing Mycotoxin Absorption: In Vivo Assessment in Pig Using Urinary Biomarkers

• DOI: 10.1021/acs.jafc.6b02146
• Publication Date: 2016-08-10T21:41:18Z
• Authors: Lucia Gambacorta; Philippe Pinton; Giuseppina Avanta...; Isabelle P. Oswald; Michele Solfrizzo
• Keywords: Fumonisin; Pomace; Ochratoxins

The efficacy of four agricultural byproducts (ABPs) and two commercial binders (CBs) to reduce the gastrointestinal absorption a mixture mycotoxins was tested in piglets using urinary mycotoxin biomarkers as indicator absorbed mycotoxins. Twenty-eight were administered bolus contaminated with containing or not ABP CB. Twenty-four hour urine collected analyzed for by multiantibody immunoaffinity-based LC-MS/MS method. Each contained 769 μg fumonisin B1 (FB1), 275 deoxynivalenol (DON), 29 zearalenone (ZEN), 6.5 aflatoxin (AFB1) 6.6 ochratoxin A (OTA) corresponding 2.2, 0.8, 0.08, 0.02, 0.02 μg/g daily diet, respectively. percentage each 50%, whereas CBs percentages 5.2 17%, 2.8, 0.3, 0.9% reduction up 69 54% ABPs CBs, White grape pomace Malvasia most effective material it reduced significantly (p < 0.05) biomarker AFB1 (67%) ZEN (69%), reductions statistically significant observed FB1 (57%), DON (40%), OTA (27%). This study demonstrates that reduces byproduct can be considered an alternative products used feed industries effective, cheap, natural binder multiple