Comparative Metabolomic and Proteomic Analyses Reveal the Regulation Mechanism Underlying MeJA-Induced Bioactive Compound Accumulation in Cutleaf Groundcherry (Physalis angulata L.) Hairy Roots

• DOI: 10.1021/acs.jafc.8b02502
• Publication Date: 2018-06-07T01:31:34Z
• Authors: Xiaori Zhan; Xinyue Liao; Xiujun Luo; Yujia Zhu; Shangguo Feng; Chunna Yu; Jiangjie Lu; Chenjia Shen; Huizhong Wang
• Keywords: Methyl jasmonate; Secondary metabolism; Metabolome; Proteome

Cutleaf groundcherry (Physalis angulata L.) is an annual plant with a number of medicinal ingredients. However, studies about the secondary metabolism P. are very limited. An integrated metabolome and proteome approach was used to reveal variations in associated bioactive compounds under methyl-jasmonate (MeJA) treatment. Application MeJA hairy roots could significantly increase accumulation most active A targeted confirmed physalins D H between treatment controls. Increases levels terpenoid backbone biosynthesis steroid related enzymes, cytochrome P450 monooxygenases 3β-hydroxysterioid dehydrogenase might provide potential explanation for MeJA-induced ingredient synthesis. Our results may contribute deeper understanding regulation mechanism underlying compound angulata.