Silver-Catalyzed Cascade Cyclization Reaction of Isocyanides with Sulfoxonium Ylides: Synthesis of 3-Aminofurans and 4-Aminoquinolines

• DOI: 10.1021/acs.orglett.0c02835
• Publication Date: 2020-09-15T11:41:10Z
• Authors: Yong-Xin Liang; Ming Yang; Bo-Wen He; Yu-Long Zhao
• Keywords: Aminoquinolines; Cascade reaction

A silver-catalyzed cascade cyclization reaction of isocyanides with sulfoxonium ylides has been developed for the first time. This provides a new and efficient method construction highly functionalized 3-aminofurans 4-aminoquinolines from readily available starting materials in single step.