Photoinduced Rapid Multicomponent Cascade Reaction of Aryldiazonium Salts with Unactivated Alkenes and TMSN3

• DOI: 10.1021/acs.orglett.0c04148
• Publication Date: 2021-02-06T13:56:41Z
• Authors: Jiabin Shen; Jun Xu; Lei He; Yani Ouyang; Lin Huang; Wanmei Li; Qing Zhu; Pengfei Zhang
• Keywords: Reaction conditions; Trimethylsilyl azide; Trimethylsilyl; Cascade reaction

The first example of a photoinduced rapid multicomponent cascade reaction aryldiazonium salts with unactivated alkenes and trimethylsilyl azide (TMSN3) under oxidant-free conditions is described. This approach provides the synthetic route for wide range unsymmetric azo compounds. compounds are obtained in good to excellent yields mild conditions. transformation applicable various alkenes, providing an alternative synthesis control experiment demonstrates that mechanism follows radical pathway.