Access to Branched Allylarenes via Rhodium(III)-Catalyzed C–H Allylation of (Hetero)arenes with 2-Methylidenetrimethylene Carbonate

• DOI: 10.1021/acs.orglett.1c01832
• Publication Date: 2021-07-21T12:45:26Z
• Authors: Shang-Shi Zhang; Yi-Chuan Zheng; Zi-Wu Zhang; Shao-Yong Chen; Hui Xie; Bing Shu; Jia-Lin Song; Yan-Zhi Liu; Yao-Fu Zeng; Luyong Zhang
• Keywords: 01 natural sciences; 0104 chemical sciences

A rhodium(III)-catalyzed C-H allylation of (hetero)arenes by using 2-methylidenetrimethylene carbonate as an efficient allylic source has been developed for the first time. Five different directing groups including oxime, N-nitroso, purine, pyridine, and pyrimidine were compatible, delivering various branched allylarenes bearing hydroxyl group in moderate to excellent yields.