Comparative Study of the Limitations and Challenges in Atom-Transfer C–H Oxidations

• DOI: 10.1021/acs.orglett.5b03047
• Publication Date: 2015-12-09T17:37:02Z
• Authors: Ashley M. Adams; J. Du Bois; Hasnain A. Malik
• Keywords: 01 natural sciences; 0104 chemical sciences

A comparative study is disclosed that seeks to highlight the current limitations and challenges exist in field of atom-transfer C–H oxidations. State-of-the-art methods are benchmarked order showcase clear differences similarities. novel Mn-mediated method for oxidation serves as a rapid simple aliphatic hydroxylation. Finally, two allow presence pyridine-containing substrates studied, something rare but great interest chemical community.