Halocyclizations of Unsaturated Sulfoximines

• DOI: 10.1021/acs.orglett.6b00958
• Publication Date: 2016-05-11T11:57:44Z
• Authors: Han Wang; Marcus Frings; Carsten Bolm
• Keywords: Iodobenzene

A method for halocyclizations of S-alkenylsulfoximines is reported. When unsaturated NH-sulfoximines are treated with a combination iodobenzene diacetate and potassium iodide, transformation to the corresponding five- six-membered cyclic products occurs providing S-oxides dihydro isothiazoles tetrahydro-1,2-thiazines, respectively, in moderate high yields good diastereoselectivities excellent regioselectivities.