Metal-Free Oxidative Annulation of 2-Naphthols with Terminal Alkynes Affording 2-Arylnaphtho[2,1-b]furans

• DOI: 10.1021/acs.orglett.6b01352
• Publication Date: 2016-06-15T17:37:59Z
• Authors: Long Liu; Xuyu Ji; Jianyu Dong; Yongbo Zhou; Shuang-Feng Yin
• Keywords: 01 natural sciences; 0104 chemical sciences

AbstractThe scalable reaction is successfully performed starting from functionalized 2‐naphthols and aryl alkynes, but fails using 1‐naphthol, phenol or biphenol and alkyl substituted or internal alkynes.