Photoredox-Catalyzed Hydroacylation of Olefins Employing Carboxylic Acids and Hydrosilanes

• DOI: 10.1021/acs.orglett.7b01391
• Publication Date: 2017-06-14T12:01:22Z
• Authors: Muliang Zhang; Rehanguli Ruzi; Junwei Xi; Nan Li; Zhongkai Wu; Weipeng Li; Shouyun Yu; Chengjian Zhu
• Keywords: Hydroacylation; Functional group; Hydrogen atom; Photoredox catalysis

A hydroacylation reaction of alkenes has been achieved employing readily available carboxylic acids as the acyl source and hydrosilanes a hydrogen via photoredox catalysis. The combination both single electron transfer atom steps dramatically expanded new applications in organic synthesis. protocol also features extremely mild conditions, broad substrate scope, good functional group tolerance, affording novel convenient approach to alkenes.