Removable Water-Soluble Olefin Metathesis Catalyst via Host–Guest Interaction

• DOI: 10.1021/acs.orglett.7b03871
• Publication Date: 2018-01-19T12:45:14Z
• Authors: Cheoljae Kim; Brian A. Ondrusek; Hoyong Chung
• Keywords: Olefin Metathesis; Salt metathesis reaction

A highly removable N-heterocyclic carbene ligand for a transition-metal catalyst in aqueous media via host–guest interactions has been developed. Water-soluble adamantyl tethered ethylene glycol the leads hydrophobic inclusion into cavity of β-cyclodextrin. Ruthenium (Ru) olefin metathesis with this demonstrated excellent performance various reactions water as well CH2Cl2, and removal residual Ru was performed filtration utilizing interaction extraction.