Copper-Catalyzed Intermolecular Carboamination of Alkenes Induced by Visible Light

• DOI: 10.1021/acs.orglett.9b00252
• Publication Date: 2019-02-25T17:30:14Z
• Authors: Yang Xiong; Xiaodong Ma; Guozhu Zhang
• Keywords: Alkene; Surface Modification; Visible spectrum

A photoinduced copper-catalyzed three-component reaction involving carbohalide, alkene and amine has been developed, leading to valuable fluoroalkyl-containing amines. sole inexpensive CuCl is used as the photo- coupling catalyst. broad array of substrates are capable partners. The diverse method compatible with a range functional groups can be further applied late-stage functionalization bioactive pharmaceuticals.