Ruthenium Catalyzed C–H Selenylations of Aryl Acetic Amides and Esters via Weak Coordination

• DOI: 10.1021/acs.orglett.9b02196
• Publication Date: 2019-08-05T13:05:06Z
• Authors: Zhengyun Weng; Xinyue Fang; Meicui He; Linghui Gu; Jiafu Lin; Zheyu Li; Wenbo Ma
• Keywords: Functional group; Coordination complex

An efficient ruthenium-catalyzed direct C-H selenylation of aryl acetic amides and esters has been achieved via distal weakly coordination. Notable features this protocol including broad substrate scope, wide functional group tolerance, good regioselectivity. In addition, diaryl disulfides were also successfully applied to reaction under slightly modified conditions.