Engineering the Redox-Driven Channel for Precisely Regulating Nanoconfined Glutathione Identification and Transport

• DOI: 10.1021/acsami.1c12061
• Publication Date: 2021-10-09T19:45:51Z
• Authors: Tianpei Guan; Ming Cheng; Lisi Zeng; Xiaoya Chen; Yuan Xie; Ziying Lei; Qiang Ruan; Jin Wang; Shuzhong Cui; Yao Sun; Haibing Li
• Keywords: Identification

Bioinspired artificial nanochannels for molecular and ionic transport have extensive applications. However, it is still a huge challenge to achieve an intelligent system with high selectivity/efficiency controllability. Inspired by glutathione across the plasma membrane via redox regulation, we herein designed fabricated redox-reactive nanochannel based on host–guest chemical strategy. The platform achieved identification transmission of in confined space. In addition, this can switch between ON OFF states through reaction. This redox-regulated provide potential application detection/binding biological analytes redox-controlled drug release.