Enhanced Corrosion Resistance and Biocompatibility of Magnesium Alloy by Mg–Al-Layered Double Hydroxide

• DOI: 10.1021/acsami.6b12974
• Publication Date: 2016-12-06T16:22:04Z
• Authors: Feng Peng; Hua Li; Donghui Wang; Peng Tian; Yaxin Tian; Guangyin Yuan; Demin Xu; Xuanyong Liu
• Keywords: Biocompatibility

Magnesium (Mg) and its alloys have been suggested as revolutionary biodegradable materials. However, fast degradation hinders clinic application. To improve the corrosion resistance biocompatibility of Mg-Nd-Zn-Zr alloy (JDBM), magnesium-aluminum-layered double hydroxide (Mg-Al LDH) was successfully introduced into Mg(OH)2 coating by hydrothermal treatment. The anions in interlayer Mg-Al LDH can be replaced chloride ions, resulting a relatively low ion concentration near surface coating. favorable proved polarization curves hydrogen collection test. significantly promoted cell adhesion, migration proliferation vitro. In addition, almost fulfilled request clinical application hemolysis ratio Finally, vivo results indicated that offered greatest long-lasting protection from triggered mildest inflammation comparing to pure coatings untreated magnesium alloy. containing present study shows promising improving anticorrosion Mg alloys, might act platform for further modification ascribed special layer structure.