Green Synthesis of Fluorescent Carbon Dots from Gynostemma for Bioimaging and Antioxidant in Zebrafish

• DOI: 10.1021/acsami.9b00074
• Publication Date: 2019-02-13T20:14:58Z
• Authors: Xinjing Wei; Li Li; Jinlong Liu; Lidong Yu; Hongbin Li; Feng Cheng; Xiaotong Yi; Jinmei He; Bingsheng Li
• Keywords: Biocompatibility; Passivation; Carbon fibers

Fluorescent carbon dots (CDs) have been synthesized via the calcination method using natural gynostemma as precursor, without any toxic ingredients or surface passivation chemicals. CDs a narrow size distribution, and mean particle is about 2.5 nm. exhibit good water dispersibility can emit intense blue fluorescence under 365 nm UV light in an aqueous solution, which be stable different conditions. The biotoxicity of on embryonic development zebrafish evaluated, hatch rate survival embryos are around 90%, malformation less than 10%. Because excellent stability biocompatibility, used for bioimaging. In addition, antioxidative stress property investigated both vitro vivo, presence promote mRNA expression related genes to encode more antioxidant proteins zebrafish. Therefore, fluorescent would potential candidate bioimaging treating diseases caused by excessive oxidation damage, such cancer, senility, other associated with aging.