Tandem Interplay of the Host–Guest Interaction and Photoresponsive Supramolecular Polymerization to 1D and 2D Functional Peptide Materials

• DOI: 10.1021/acsami.9b09690
• Publication Date: 2019-07-15T19:33:04Z
• Authors: Jojo P. Joseph; Ashmeet Singh; Deepika Gupta; Chirag Miglani; Asish Pal
• Keywords: Moiety; Dispersity

Peptide 1 with an Aβ42 amyloid nucleating core and a photodimerizable 4-methylcoumarin moiety at its N terminus demonstrates the step-wise self-assembly in water to form nanoparticles, eventual transformation into 1D nanofibers. Addition of γ-cyclodextrin subsequent irradiation UV light 320 nm resulted morphological conversion free-standing 2D nanosheets mediated by host-guest interaction. Mechanical agitation nanostructures led seeds narrow polydispersity indices, which mediation seeded supramolecular polymerization found seamless control over dimensions nanostructures. Such structural temporal differentiate pathway was exploited tune mechanical strength hierarchical hydrogel materials. Finally, dimensional characteristics positively charged peptide fibers sheets were envisaged as excellent exfoliating agents for inorganic hybrid materials, example, MoS2.