Synthesis of Benz-Fused Azoles via C-Heteroatom Coupling Reactions Catalyzed by Cu(I) in the Presence of Glycosyltriazole Ligands

• DOI: 10.1021/acscombsci.9b00004
• Publication Date: 2019-04-03T22:13:23Z
• Authors: Nidhi Mishra; Anoop S. Singh; Anand K. Agrahari; Sumit K. Singh; Mala Singh; Vinod K. Tiwari
• Keywords: Heteroatom

Glycosyl triazoles are conveniently accessible and contain multiple metal-binding units that may assist in metal-mediated catalysis. Azide derivatives of d-glucose have been converted to their respective aryltriazoles screened as ligands for the synthesis 2-substituted benz-fused azoles benzimidazoquinazolinones by Cu-catalyzed intramolecular Ullmann type C-heteroatom coupling. Good excellent yields a variety heterocyles were obtained this readily catalytic system.