Wastewater-Based Surveillance of Respiratory Syncytial Virus Epidemic at the National Level in Finland

• DOI: 10.1021/acsestwater.3c00752
• Publication Date: 2024-05-09T13:03:50Z
• Authors: Annika Länsivaara; Kirsi-Maarit Lehto; Rafiqul Hyder; Oskari Luomala; Anssi Lipponen; Anna-Maria Hokajärvi; Annamari Heikinheimo; Tarja Pitkänen; Sami Oikarinen
• Keywords: 0303 health sciences; 03 medical and health sciences; respiratory syncytial virus; environmental surveillance; wastewater-based surveillance; epidemiology; infectious diseases; epidemic; Public health care science, environmental and occupational health

The purpose of this study was to evaluate the potential wastewater-based surveillance in monitoring epidemics at national level Finland. 2021–2022 respiratory syncytial virus epidemic Finland analyzed from wastewater and Finnish National Infectious Diseases Register. performed using 150 samples that were collected monthly May 2021 July 2022 ten treatment plants cover 40% population. Respiratory detection 24 h composite influent reverse-transcription quantitative polymerase chain reaction (RT-qPCR). data positively correlated with Register-based sampling week incidence (correlation coefficient, CC min = 0.412, max 0.865) four-week cumulative (CC 0.482, 0.814), showing estimating course epidemics. When register-based least four cases/100,000 persons/sampling week, it detected all samples. This showed can be used surveil level, its other should explored further.