Expanding Bromodomain Targeting into Neglected Parasitic Diseases

• DOI: 10.1021/acsinfecdis.1c00387
• Publication Date: 2021-10-07T02:07:59Z
• Authors: Cynthia Tallant; Paul Bamborough; Chun-wa Chung; Francisco Javier ...; Robert Kirkpatrick; Chris Larminie; Julio Martín; Rab Prinjha; Inmaculada Rioja; Daniel F. Simola; Raquel Gabarró; Félix Calderón
• Keywords: Neglected Tropical Diseases; Antiparasitic agent

This Perspective discusses the published data and recent developments in research area of bromodomains parasitic protozoa. Further work is needed to evaluate tractability this target class context infectious diseases launch drug discovery campaigns identify develop antiparasite drugs that can offer differentiated mechanisms action.