Temperature Self-Calibration of Always-On, Field-Deployed Ion-Selective Electrodes Based on Differential Voltage Measurement

• DOI: 10.1021/acssensors.2c01163
• Publication Date: 2022-09-08T18:07:06Z
• Authors: Ajanta Saha; Aiganym Yermembetova; Ye Mi; Sarath Gopalakris...; Sotoudeh Sedaghat; Jose Waimin; Pengcheng Wang; Nicholas Glassmaker; Charilaos Mousoulis; Nithin Raghunathan; Saurabh Bagchi; Rahim Rahimi; Ali Shakouri; Alexander Wei; Muhammad A. Alam
• Keywords: ISFET; Potentiometric sensor; Ion selective electrode; Thermometer

Originally developed for use in controlled laboratory settings, potentiometric ion-selective electrode (ISE) sensors have recently been deployed continuous, situ measurement of analyte concentration agricultural (e.g., nitrate), environmental ocean acidification), industrial wastewater), and health-care sectors sweat sensors). However, due to uncontrolled temperature lack frequent calibration these field applications, it has difficult achieve accuracy comparable the setting. In this paper, we propose a novel self-calibration method where ISE can serve as their own thermometer therefore precisely measure condition by compensating variations. We validate with experiments using pH nitrate ISEs, which Nernst principle electrochemical sensing. show that, self-calibration, be measured within 0.3% 5% true concentration, respectively, under varying concentrations conditions. Moreover, perform study continuously monitor an over period 6 days. Our approach determines 4% ground truth laboratory-based high-precision sensors. is general would allow battery-free temperature-corrected all principle-based being wearable or implantable