Influence of Hyperbranched Multi-methacrylates for Dental Neat Resins on Proliferation of Human Gingival Fibroblasts

• DOI: 10.1021/bm000101p
• Publication Date: 2002-07-26T04:54:32Z
• Authors: Qichun Wan; Deborah Rumpf; Scott R. Schricker; Angelo Mariotti; Bill M. Culbertson
• Keywords: Biocompatibility; Polystyrene; Triethylene glycol; Dental composite; Acrylic resin

We have previously shown that hyperbranched multi-methacrylate (H-MMA)-modified dental resins VLC activities, lower polymerization shrinkage, and improved mechanical properties, compared to the 2,2-bis[4-(2-hydroxy-3-methacryloyolxypropoxy)phenyl]propane/triethyleneglycol dimethacrylate (BisGMA/TEGDMA) neat resin. The results are due unique molecular structure high weight of H-MMA intermediates. purpose this study was evaluate biocompatibility H-MMA-modified resins. cell proliferation three human gingival fibroblast strains on either H-MMA, BisGMA/TEGDMA, or a polystyrene disk examined. Following 10 days proliferation, there no statistical difference in number between unmodified resin disks. had less free monomer leaching than but showed similar properties water sorption contact angle values. All these suggest is as good commercially used BisGMA/TEGDMA has potential applications composites.