Flow Through, Immunomagnetic Cell Separation

• DOI: 10.1021/bp970140l
• Publication Date: 2002-07-26T05:19:13Z
• Authors: J.J. Chalmers; M. Zborowski; L. Sun; L. Moore
• Keywords: Separator (oil production); Immunomagnetic separation

A brief, process-oriented overview of immunologically based cell separation technology is presented. In addition, the design and preliminary experimental data two unique flow-through immunomagnetic devices are The first on a dipole magnetic field, while second basis quadrupole field. can "fractionate" an inlet, magnetically labeled, stream into different outlet streams degree to which immunomagnetically labeled. separator splits in purity, recovery, potentially cells labeled controlled by flow rates inlet flows. 99% purity 86% recovery have been achieved with this system. Some distinct advantages these systems potential high throughput at cost significantly lower than current, comparable technologies.