Supramolecular Reinforcement of a Large-Pore 2D Covalent Organic Framework

• DOI: 10.1021/jacs.1c12020
• Publication Date: 2022-01-31T17:48:07Z
• Authors: Shashini D. Diwakara; Whitney S. Y. Ong; Yalini H. Wijesun...; Robert L. Gearhart; Fabian C. Herbert; Sarah G. Fisher; Gregory T. McCand...; Sampath B. Alahakoon; Jeremiah J. Gasse...; Sheel C. Dodani; Ronald A. Smaldone
• Keywords: Covalent organic framework; Non-covalent interactions

Two-dimensional covalent organic frameworks (2D-COFs) are a class of crystalline porous polymers that consist covalently linked, two-dimensional sheets can stack together through noncovalent interactions. Here we report the synthesis novel COF, called PyCOFamide, which has an experimentally observed pore size is greater than 6 nm in diameter. This among largest reported to date for 2D-COF. PyCOFamide exhibits permanent porosity and high crystallinity as evidenced by nitrogen adsorption, powder X-ray diffraction, high-resolution transmission electron microscopy. We show large enough accommodate fluorescent proteins such Superfolder green protein mNeonGreen. work demonstrates utility structural reinforcement 2D-COFs produce larger persistent sizes previously possible.