Folding-Generated Molecular Tubes Containing One-Dimensional Water Chains

• DOI: 10.1021/jacs.5b11808
• Publication Date: 2015-12-18T22:26:43Z
• Authors: Hae-Geun Jeon; Jin Young Jung; Philjae Kang; Moon-Gun Choi; Kyu-Sung Jeong
• Keywords: Folding (DSP implementation); Ribbon

A series of indolocarbazole-pyridine (IP) oligomers were prepared that fold into helical conformations, and their folding features in solution the solid state revealed. Helical these IP foldamers is induced by dipolar interactions through ethynyl bond π-stacking between two repeating units. Upon folding, (1)H NMR signals aromatic protons significantly shifted upfield Δδ = 0.5-2.2 ppm. In addition, hypochromic shifts fluorescence quenching observed absorption emission spectra. X-ray crystal structures clearly demonstrated folded to with cylindrical internal cavities wherein 3 or 5 water molecules occupied hydrogen-bonding a 1-D array, reminiscent transmembrane channels, called aquaporins.