Dietary cholesterol impairs memory and memory increases brain cholesterol and sulfatide levels.

• DOI: 10.1037/a0018253
• Publication Date: 2010-02-08T22:54:52Z
• Authors: Deya S. Darwish; Desheng Wang; Gregory W. Konat; Bernard G. Schreurs
• Keywords: Eyeblink conditioning

Cholesterol and sulfatides play many important roles in learning memory. To date, our observations about the effects of cholesterol on have been assessed during response acquisition; that is, a new Here, we report for first time to knowledge, effect diet previously formed Rabbits were given trace conditioning nictitating membrane 10 days, then fed 2% 8 weeks, memory recall initially learned task. We show dietary had an adverse recall. Second, investigated whether caused increase brain sulfatide levels four major structures (hippocampus, frontal lobe, brainstem, cerebellum) using technique analyzing myelin myelin-free fractions separately. Although data confirm previous findings does not directly affect establish it brain, these did rather significantly hippocampus lobe as function