The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia

• DOI: 10.1038/leu.2017.194
• Publication Date: 2017-06-20T06:40:27Z
• Authors: A Rio-Machin; G Gómez-López; J Muñoz; F Garcia-Martinez; A Maiques-Diaz; S Alvarez; R N Salgado; M Shrestha; R Torres-Ruiz; C Haferlach; M J Larráyoz; M J Calasanz; J Fitzgibbon; J C Cigudosa
• Keywords: Pathogenesis

unchanged over this period when adjusted for age, stage at diagnosis, time from diagnosis to transplant and disease status transplant.VRD has become the most common pretransplant induction regimen after 2010.Only, half of patients are placed on post-transplant treatment day 100 AHCT, with lenalidomide as frequently used agent.Counterintuitively, we did not see an increase in use maintenance recent period.Despite these impressive gains field, progression MM remains frequent cause death.