Visit-to-visit systolic blood pressure variability in patients with ST-elevation myocardial infarction predicts long-term cardiovascular outcomes

• DOI: 10.1038/s41371-019-0176-0
• Publication Date: 2019-02-18T13:03:00Z
• Authors: Moon-Seung Soh; Jin-Sun Park; Kyoung-Woo Seo; Hyoung-Mo Yang; Hong-Seok Lim; Byoung-Joo Choi; So-Yeon Choi; Myeong-Ho Yoon; Gyo-Seung Hwang; Seung-Jea Tahk; Joon-Han Shin
• Keywords: Mace

Elevated visit-to-visit blood pressure variability (BPV), independent of mean BP, has been associated with cardiovascular events. However, its impact after ST-elevation myocardial infarction (STEMI) not established. This study aimed to investigate the prognostic BPV on patients STEMI. We analyzed data and clinical outcomes STEMI survivors who underwent successful primary coronary intervention from 2003 2009. BP was measured at discharge 1, 3, 6, 12, 24, 36 months, we calculated as intra-individual standard deviations (SDs) systolic (SBP) across these measurements. classified high low-BPV group, evaluated outcomes: occurrence major adverse events (MACEs), death, recurrent infarction, target vessel revascularization within 60 months. enrolled 343 patients, follow-up duration 68 ± 34 months (median: 76 months). Mean median SBP SDs were 13.2 12.3 mmHg, divided into one two groups based (high-BPV group = SD ≥ mmHg; < mmHg). The MACE-free survival in high-BPV significantly worse than that (log-rank p 0.035). For risk a MACE increased by 57% (95% confidence interval: 1.03-2.39; 0.038). Visit-to-visit rates Careful assessment attempts reduce might be also important survivors.