Dnmt1 links BCR-ABLp210 to epigenetic tumor stem cell priming in myeloid leukemia

• DOI: 10.1038/s41375-018-0192-z
• Publication Date: 2018-06-28T13:33:46Z
• Authors: Carolina Vicente-...; Inés González-Her...; Lalit Sehgal; Idoia García-Ramírez; Guillermo Rodrígu...; Belén Pintado; Oscar Blanco; Francisco Javier ...; María Begoña Garc...; Michael R. Green; Isidro Sánchez-Ga...
• Keywords: DNA (Cytosine-5-)-Methyltransferase 1; 0303 health sciences; Gene Expression Regulation, Leukemic; Fusion Proteins, bcr-abl; Mice, Transgenic; DNA Methylation; Brief Communication; Cellular Reprogramming; Epigenesis, Genetic; 3. Good health; Mice; 03 medical and health sciences; Leukemia, Myeloid; Neoplastic Stem Cells; Animals; Humans

Research in CVD group is partially supported by FEDER, “Miguel Servet” Grant (CP14/00082 - AES 2013-2016) from the Instituto de Salud Carlos III (Ministerio Economia y Competitividad), “Fondo Investigaciones Sanitarias/Instituto III” (PI17/00167), and Lady Tata International Award for Leukaemia 2016–2017. ISG FEDER MINECO (SAF2012-32810, SAF2015-64420-R Red Excelencia Consolider OncoBIO SAF2014-57791- REDC), (PIE14/00066), ISCIII- Plan Ayudas IBSAL 2015 Proyectos Integrados (IBY15/00003), Junta Castilla Leon (BIO/SA51/15, CSI001U14, UIC-017, CSI001U16), German Carreras Foundation (DJCLS R13/26). lab a member of EuroSyStem DECIDE Network funded European Union under FP7 program. IGR was BES-Ministerio Competitividad (BES2013-063789). GRH FSE-Conserjeria Educacion la (CSI001-15).