Relationship between traditional risk factors for hypertension and systolic blood pressure in the Tohoku Medical Megabank Community-based Cohort Study

• DOI: 10.1038/s41440-024-01582-1
• Publication Date: 2024-02-29T11:02:17Z
• Authors: Masato Takase; Naoki Nakaya; Kozo Tanno; Mana Kogure; Rieko Hatanaka; Kumi Nakaya; Ippei Chiba; Ikumi Kanno; Kotaro Nochioka; Naho Tsuchiya; Tomohiro Nakamura; Takumi Hirata; Taku Obara; Mami Ishikuro; Yuka Kotozaki; Akira Uruno; Tomoko Kobayashi; Eiichi N. Kodama; Yohei Hamanaka; Masatsugu Orui; Soichi Ogishima; Satoshi Nagaie; Hideki Ohmomo; Nobuo Fuse; Junichi Sugawara; Atsushi Shimizu; Yoko Izumi; Shinichi Kuriyama; Atsushi Hozawa
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Article

Abstract Risk factors for hypertension have been emphasized in the Japanese Society of Hypertension Guidelines Management Hypertension. However, large-scale studies on association smoking, potassium excretion, and gamma-glutamyl transferase level with BP population are limited. We conducted a cross-sectional study to examine between risk systolic blood pressure Tohoku Medical Megabank Community-based Cohort Study (23,446 men 38,921 women aged ≥20 years). A model adjusted age, body mass index, smoking status, drinking estimated daily salt intake, (or urinary sodium-to-potassium ratio), transferase, physical activity, education level, status damage homes during Great East Japan Earthquake, residential areas was used. The average age were 62.5 (10.3) years 59.6 (11.3) women, 128.9 (16.7) mmHg 124.7 (17.5) respectively. Body index ratio levels positively associated pressure. Compared never-drinkers, current drinkers who consumed 23–45 g/day ≥46.0 had significantly increased Conversely, smokers (1-10 cigarettes/day 11-20 cigarettes/day) inversely compared never-smokers. Overall, factors, including alcohol consumption, ratio, excretion. Our findings support notion that lifestyle modifications should be attempted prevent hypertension.