TaTCP6 is required for efficient and balanced utilization of nitrate and phosphorus in wheat

• DOI: 10.1038/s41467-025-57008-0
• Publication Date: 2025-02-16T10:47:41Z
• Authors: Bin Liu; Weiya Xu; Yanxiao Niu; Qiuyuan Li; Beilu Cao; Jingyi Qi; Yidi Zhao; Yilan Zhou; Long Song; Dongkai Cui; Zhenshan Liu; Mingming Xin; Yingyin Yao; Mingshan You; Zhongfu Ni; Qixin Sun; Jiewen Xing
• Keywords: Science; Q

High crop yields require adequate nutrients, particularly nitrate (N) and phosphorus (P). Identifying regulators for efficient N-P utilization is critical in wheat. To explore interactions, we analyze root transcriptomes under varying supplies identify TaTCP6 as a potential regulator. Nitrate-stimulated directly triggers the expression of genes related to nitrogen utilization. competes with TaSPX1/4 release TaPHR2, also interacts TaPHR2 enhance transactivation capacity downstream genes. Thus, through dual roles TaTCP6, TCP6-SPX-PHR2 module activates starvation response (PSR) Inhibiting reduces N P absorption, negatively impacting yield, while overexpressing increases grain yield. Notably, overexpression TaSPX1 suppresses genes, especially low conditions. In conclusion, our findings highlight role coordinating propose strategy reduce fertilizer inputs sustainable agriculture. A nitrate-induced transcription factor identified central regulator balanced phosphorus, moderate increase its promotes wheat