Systematic review of the use of ultrasound for venous assessment and venous thrombosis screening in spaceflight

• DOI: 10.1038/s41526-024-00356-w
• Publication Date: 2024-02-05T14:02:17Z
• Authors: Antoine Elias; Tobias Weber; David A. Green; Katie M. Harris; Jonathan M. Laws; Danielle K. Greaves; David S. Kim; Lucia Mazzolai-Du...; Lara Roberts; Lonnie G. Petersen; Ulrich Limper; Andrej Bergauer; Michael Elias; Andrew Winnard; Nandu Goswami
• Keywords: Spaceflight; Modalities; Valsalva maneuver

The validity of venous ultrasound (V-US) for the diagnosis deep vein thrombosis (DVT) during spaceflight is unknown and difficult to establish in diagnostic accuracy management studies this context. We performed a systematic review use V-US upper-body system identify microgravity-related changes effect interventions reverse them, assess appropriateness with terrestrial standards. An tool was developed following expert panel discussions studies, including criteria relevant crew experience, in-flight equipment, assessment sites, modalities, DVT diagnosis. Microgravity-related findings reported as an increase internal jugular (IJV) cross-sectional area pressure were associated reduced, stagnant, retrograde flow. Changes on average responsive using lower body negative pressure, Bracelets, Valsalva Mueller manoeuvres, contralateral IJV compression. In comparison standards, did not meet all criteria. (n = 3), single only modality criterion met other 15), appropriate except experience criterion, which four studies. Future practice research should account changes, evaluate individual interventions, adopt Earth-based