Prognostic performance of three lymph node staging schemes for patients with Siewert type II adenocarcinoma of esophagogastric junction

• DOI: 10.1038/s41598-017-09625-z
• Publication Date: 2017-08-25T08:49:16Z
• Authors: Jinming Xu; Jinlin Cao; Luming Wang; Zhitian Wang; Yiqing Wang; Yihua Wu; Wang Lv; Jian Hu
• Keywords: Akaike information criterion; Statistic

The prognostic performance of different lymph node staging schemes for adenocarcinoma esophagogastric junction (AEG) remains controversial. objective the present study was to compare efficacy number metastases (LNMs), positive ratio (LNR) and log odds nodes (LODDS). Patients diagnosed with Siewert type II AEG were included from Surveillance, Epidemiology, End Results database. Harrell's C-index statistic, Schemper's proportion explained variation (PEV), Akaike information criterion (AIC) restricted cubic spine analyses adopted assess predictive accuracy LNM, LNR LODDS. A total 1302 patients post-surgery included. LODDS all showed significant value in multivariate Cox regression analyses. performed higher than LNM LNR, relatively C-index, PEV lower AIC value. For no involved, still significantly discriminatory utility. more accurate AEG, it could help detect survival heterogeneity involved.