Malaria transmission in landscapes with varying deforestation levels and timelines in the Amazon: a longitudinal spatiotemporal study

• DOI: 10.1038/s41598-021-85890-3
• Publication Date: 2021-03-19T13:04:20Z
• Authors: Gabriel Z. Laporta; Roberto C. Ilacqua; Eduardo S. Bergo; Leonardo S. M. Ch...; Sheila R. Rodovalho; Gilberto G. Moresco; Elder A. G. Figueira; Eduardo Massad; Tatiane M. P. de ...; Sara A. Bickersmith; Jan E. Conn; Maria Anice M. Sa...
• Keywords: Deforestation; Forest cover; Land Cover

Abstract The relationship between deforestation and malaria is a spatiotemporal process of variation in Plasmodium incidence human-dominated Amazonian rural environments. present study aimed to assess the underlying mechanisms malarial exposure risk at fine scale 5-km 2 sites across Brazilian Amazon, using field-collected data with longitudinal spatiotemporally structured approach. Anopheline mosquitoes were sampled from 80 investigate infection rate mosquito communities estimate landscapes. remaining amount forest cover (accumulated deforestation) timeline estimated each site represent main parameters both frontier hypothesis an alternate scenario, deforestation-malaria hypothesis, proposed herein. maximum frequency pathogenic occurred intermediate level (50% accumulated two temporal peaks, e.g., 10 35 years after beginning organization settlement. density infected anophelines where original decreased by more than 50% first 25 settlement development was least twice as high calculated for other studied (adjusted ratio = 2.25; 95% CI, 1.38–3.68; p 0.001). results this support unifying explaining emergence designing specific control interventions Amazon.