Acoustic-like dynamics of amorphous drugs in the THz regime

• DOI: 10.1038/srep02518
• Publication Date: 2013-08-30T09:15:44Z
• Authors: E. A. A. Pogna; C. Rodríguez-Tinoco; M. Krisch; J. Rodríguez-Viejo; T. Scopigno
• Keywords: Dynamics; Acoustic attenuation

Abstract The high frequency dynamics of Indomethacin and Celecoxib glasses has been investigated by inelastic x-ray scattering, accessing a momentum-energy region still unexplored in amorphous pharmaceuticals. We find evidence phonon-like acoustic determine the THz behavior sound velocity attenuation. Connections with ordinary propagation are discussed, along relation between fast slow degrees freedom as represented non-ergodicity factor kinetic fragility, respectively.