Lack of effects on key cellular parameters of MRC-5 human lung fibroblasts exposed to 370 mT static magnetic field

• DOI: 10.1038/srep19398
• Publication Date: 2016-01-14T14:14:48Z
• Authors: Stefania Romeo; Anna Sannino; Maria Rosaria Scarfì; Rita Massa; Raffaele d’Angelo; Olga Zeni
• Keywords: Human lung

Abstract The last decades have seen increased interest toward possible adverse effects arising from exposure to intense static magnetic fields. This concern is mainly due the wider and applications of such fields in industry clinical practice; among them, Magnetic Resonance Imaging (MRI) facilities are main sources for both general public (patients) workers. In recent investigations, exposures been demonstrated elicit, different cell models, permanent transient modifications cellular endpoints critical carcinogenesis process. World Health Organization has therefore recommended vitro investigations as important research need, be carried out under strictly controlled conditions. Here we report on absence viability, reactive oxygen species levels DNA integrity MRC-5 human foetal lung fibroblasts exposed 370 mT induction level, regimens. Exposures performed by using an experimental apparatus designed realized operating with field generated magnets confined a circuit, allow cultures confounding factors like heating or electric components.