Assessment of Fat distribution and Bone quality with Trabecular Bone Score (TBS) in Healthy Chinese Men

• DOI: 10.1038/srep24935
• Publication Date: 2016-04-26T09:10:10Z
• Authors: Shan Lv; Aisen Zhang; Wenjuan Di; Yunlu Sheng; Peng Cheng; Hanmei Qi; Juan Liu; Jing Yu; Guoxian Ding; Jinmei Cai; Bin Lai
• Keywords: Trabecular bone score; Fat distribution

Whether fat is beneficial or detrimental to bones still controversial, which may be due inequivalence of the mass. Our objective define effect body and its distribution on bone quality in healthy Chinese men. A total 228 men, aged from 38 89 years, were recruited. BMD, trabecular score (TBS), measured by dual-energy X-ray absorptiometry. Subcutaneous visceral assessed MRI. In Pearson correlation analysis, lumbar spine BMD exhibited positive associations with all regional depots, regardless distribution. However, disappeared adjusted covariables age, BMI, HDL-C, HbA1c%. TBS was negatively correlated multiple linear regression models, android (and not gynoid, trunk, limbs fat) showed significant inverse association (β = -0.611, P < 0.001). Furthermore, described as a pathogenic harmful TBS, even after adjusting for age BMI -0.280, 0.017). findings suggested that mass, especially fat, have negative effects microstructure; whereas mass contributes through mechanical loading.