Synthesis, crystal structure and superoxide dismutase activity of a five-co-ordinated manganese(II) complex

• DOI: 10.1039/a707433f
• Publication Date: 2002-07-26T09:19:28Z
• Authors: Dao Feng Xiang; Chun Ying Duan; Xiang Shi Tan; Qin Wei Hang; Wen Xia Tang
• Keywords: 01 natural sciences; 0104 chemical sciences

A five-co-ordinate manganese(II) complex [Mn(ntb)(Hsal)][ClO4], where ntb is tris(benzimidazol-2-ylmethyl)amine and Hsal– is the anion of salicyclic acid (H2sal), has been prepared and characterized by X-ray crystallography. The manganese adopts a distorted trigonal-bipyramidal co-ordination geometry with a N4O ligand donor set and bears structural similarities to the active site of manganese superoxide dismutase. The electro-chemical properties of the complex were studied in MeCN by cyclic voltammetry. The complex can catalyse the dismutation of superoxide (O2–) effectively in the riboflavin–methionine–nitro blue tetrazolium assay.