Nearly monodispersed core–shell structural Fe3O4@DFUR–LDH submicro particles for magnetically controlled drug delivery and release

• DOI: 10.1039/c0cc01313g
• Publication Date: 2010-11-16T09:30:30Z
• Authors: Dengke Pan; Hui Zhang; Ting Fan; Jiangang Chen; Xue Duan
• Keywords: Antimetabolites, Antineoplastic; Magnetics; Drug Delivery Systems; Hydroxides; Floxuridine; 01 natural sciences; Ferrosoferric Oxide; 0104 chemical sciences; 3. Good health

Nearly monodispersed magnetic Fe(3)O(4)@DFUR-LDH submicro particles containing the anticancer agent DFUR were prepared via a coprecipitation-calcination-reconstruction strategy of LDH materials over the surface of Fe(3)O(4) particles, and present well-defined core-shell structure, strong magnetization and obvious magnetically controlled drug delivery and release properties.