Phosphine-catalyzed highly diastereoselective [3+2] cyclization of isatin derived electron-deficient alkenes with α-allenic esters

• DOI: 10.1039/c0cc04289g
• Publication Date: 2010-11-26T10:30:24Z
• Authors: Xiu-Chun Zhang; Shu-Hua Cao; Yin Wei; Min Shi
• Keywords: Isatin

A novel phosphine-catalyzed highly diastereoselective [3+2] cycloaddition of isatin derived α,β-unsaturated ketones with α-allenic ester has been developed.